Found 32 matching trials
SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients PHASE2 Open label multicentric randomized phase II trial, using high throughput ge...
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Centre Hospitalier Henri Duffau
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AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies PHASE1 The primary purpose of the study is to assess the safety, tolerability and ...
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Active Not Recruiting
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Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies PHASE2 Background:
\- The current standard of care for advanced lung cancer and c...
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National Institutes of Health Clinical Center
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To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers PHASE1 Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
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Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD) PHASE2 Phase 2 Platform Study in Patients with Advanced Non-Small Lung Cancer who ...
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Active Not Recruiting
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Selumetinib and Azacitidine in High Risk Chronic Blood Cancers PHASE1 This is a phase I, open-label, dose-escalation study to determine the MTD o...
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The University of Chicago
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Study of MK-8353 + Selumetinib in Advanced/Metastatic Solid Tumors (MK-8353-014) PHASE1 This is a multicenter, worldwide, open-label study of MK-8353 in combinatio...
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Florida Cancer Specialists ( Site 7000)
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To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers PHASE1 Study to assess the effect of Rifampicin on the pharmacokinetics of Selumet...
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Investigate the Safety and Tolerability of AZD6244 Monotherapy or + Docetaxel in Japanese Patients With Advanced Solid Malignancies or Non-Small Cell Lung Cancer PHASE1 The objective of this study will be to investigate the safety and tolerabil...
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Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC PHASE3 The purpose of this study is to assess the efficacy of selumetinib in combi...
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Active Not Recruiting
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